The Fulham defender twisted his knee in his side’s 1-2 loss to Chelsea and has been ruled out for six weeks as a result.
Ghana team told KickoffGhana.com in Nelspruit that they will settle on a replacement by close of work on Wednesday and also decide on whether to call withdraw John Mensah from the squad completely.
The injuries are wrecking Ghana’s ambitions with Stephen Appiah and Laryea Kingston already out.
Paintsil’s absence takes out a huge chunk of experience from the squad but Rajevac will be confident his pet player Samuel Inkoom can deputise for him well.