Midfielder Kwadwo Asamoah is absent through injury after originally being named in the squad while Hearts of Scotland want Laryea Kingston out claiming the club will need him well rested for the coming season.
But kickoffGhana.com understands Ghana will not budge so long as the player is well and fit to play on a day many other countries will be involved in international football.
Kingston has been absent from the last three games for Ghana and could be making his return on Wednesday.
The Ghana squad will begin assembling in London on Monday and will hold only one meaningful training session on Tuesday ahead of the friendly.
Milovan Rajevac who has combined his holidays with player monitoring will join up with the team from his Serbia base.