Coach Otto Addo has named 24 players for the final stretch, blending key returnees with the regular squad.
Abdul Fatawu Issahaku has earned a recall to Ghana’s squad after impressing for Leicester City in the English Championship.
The winger had been out of action since November with an ACL setback but has now returned in strong form.
Defender Alidu Seidu also rejoins the team, recovering from a knee injury that sidelined him for nearly a year.
Another returnee is defender Ebenezer Annan, who missed the previous call-up but has now been reinstated, replacing Derrick Arthur.
The Black Stars will face the Central African Republic on October 8 at the Stade d’Honneur de Meknes before hosting Comoros at the Accra Sports Stadium on October 12.
With 19 points already secured, Ghana sits top of Group I and needs to finish strongly to secure a fifth World Cup qualification.
