Stella Nyamekye’s strike in the 18th minute gave them the lead at halftime.
After the break, Ghana maintained control of the game, scoring a second goal through Nancy Amoah.
Ghana must now prepare for the second leg scheduled for June 4.
The Maidens are aiming for a record seventh FIFA U17 Women’s World Cup appearance.
And they did so by avoiding complacency and achieving a significant victory.